Proliant Inc.
Health Division
Meat Ingredients Dairy Ingredients Health Biologicals
Meat Ingredients Dairy Ingredients Health Biologicals
Ingredients
Top Spacer
Line Spacer
Immunolin
Line Spacer
NutraGammax
Line Spacer
Glossary
Line Spacer
Bottom Spacer
Line Spacer
Product Applications
Line Spacer
Health Consumer Products List
Line Spacer
Latest Research
Line Spacer
Health Links
Line Spacer
Marketing Events
Line Spacer
Company Services
Line Spacer
Manufacturing Plants
Line Spacer
News / Press Releases
Line Spacer
Proliant In The Press
Line Spacer
Videos
Line Spacer
Request More Information
  

NutraGammax: The "What's New" in Protein Sources
1. What is NutraGammax?  View this information in PDF format.

NutraGammax is a >90% serum protein isolate. It is also the first new protein source to come to the protein market in many years. Unlike traditional sources of protein such as casein or whey, NutraGammax is rich in naturally occurring, bioactive proteins and peptides. The bioactivity of the proteins and peptides offers the athlete benefits beyond an excellent amino acid profile.

2. Is there science to support the use of NutraGammax in sports nutrition?

If the processing technology would have existed, this product should have been launched many years ago because the basic science behind the product is strong. NutraGammax is a concentrate of serum, the gold-standard of all natural substances in supporting cell growth and proliferation. Human cells absolutely thrive when the media contains bovine serum. But, the idea for NutraGammax is founded on more than 50 studies that have been published in animal sciences demonstrating that plasma protein supplementation promotes growth, particularly lean tissue growth. Recent clinical studies of colostrum, a very similar substance to serum, support the concept. Antonio et al. reported improvements in bone-free lean body mass when active adults received 20 g/d of colostrum vs a control group that consumed whey. NutraGammax delivers even more of the key bioactives in colostrum at a much lower cost. (A complete set of references is available). Clinical studies in children support the safety of product (1;2)

3. What is the mode of action?

NutraGammax, due to its consistent, high concentration of immunoglobulins, has been shown to boost immunity and increase lean tissue accretion in animal studies (3-8). But, the most exciting aspect of the NutraGammax science is new studies that demonstrate a positive effect on inflammatory cytokine production and expression (9). The effects of NutraGammax on inflammatory cytokine production provides a partial explanation of how NutraGammax can promote lean tissue accretion and amino acid utilization while reducing amino acid catabolism. Recent studies of the biological roles of cytokines have opened up a new opportunity towards maximizing protein retention and lean body mass in the athlete (11-18). In addition to promoting inflammation, cytokines also elicit potent catabolic effects on skeletal muscle (19) which affects growth (20-22). Cytokine management, because of its potential to affect the catabolic component of physiological state and to reduce inflammatory mediators, has tremendous promise towards increasing lean body mass and reducing muscle soreness.

4. How does NutraGammax compare to other proteins?

Comparing NutraGammax to other proteins is like comparing apples and oranges. Both are fruit but they are each good in some ways and not in others. Basically, NutraGammax is a protein source with neutral taste, excellent solubility, and similar price to egg albumen. However, NutraGammax differs completely in purpose of use to other protein sources. Proteins like albumin, casein and whey can be used as sole sources of dietary protein due to a highly available, balanced, essential amino acid profile but these proteins have negligible bioactivity. NutraGammax, on the other hand, is rich in bioactive proteins, which helps promote amino acid utilization (6;8;10). The proteins are larger and more complex in structure than whey or casein (see accompanying SDS-PAGE) with a slow rate of digestion, which allows them to retain biological activity. Ideally, NutraGammax should be combined with whey or other high quality protein sources lower in molecular weight with a more rapid rate of digestion. Retaining biological activity is critical to the dual-benefit of promoting lean tissue growth and amino acid utilization while also supporting immunity.

5. How should NutraGammax be used?

For best results NutraGammax should be consumed in protein powders, bars or beverages at a rate of 25% of the protein in the product or, for maximum effect, 10 - 20 g of NutraGammax per day. It can be used in both post-workout (fast-digestion) and meal replacement (slow digestion) products. Athletes using both resistance and endurance training may benefit because of the positive effects on protein utilization and the opportunity for cytokine modulation. Methionine is the limiting amino acid in NutraGammax. For best results, NutraGammax should be a part of a complete, balanced nutritional program.

Reference List: (A complete set of references is available)
  • Brown KH, Santizo M-C, Begin F, Torun B. Effect of supplementation with multiple micro-nutrients (MMN) and/or bovine serum concentrate (BSC) on the growth of low-income, peri-urban Guatemalan infants and young children. FASEB Journal 2000;14:A534 (abstr).
  • Lembcke JL, Peerson JM, Brown KH. Acceptability, safety, and digestibility of spray-dried bovine serum added to diets of recovering malnourished children. J Pediatr.Gastroenterol.Nutr 1997;25:381-4.
  • Coffey RD, Cromwell GL. Use of spray-dried animal plasma in diets for weanling pigs. Pig News and Information 2001;22:39-48.
  • Hansen JA, Nelssen JL, Goodband RD, Weeden TL. Evaluation of animal protein supplements in diets of early-weaned pigs. J Anim.Sci 1993;71:1853-62.
  • Jiang R, Chang X, Stoll B et al. Dietary plasma protein reduces small intestinal growth and lamina propria cell density in early weaned pigs. J.Nutr. 2000;130:21-6.
  • Jiang R, Chang X, Stoll B et al. Dietary plasma protein is used more efficiently than extruded soy protein for lean tissue growth in early-weaned pigs. J.Nutr. 2000;130:2016-9.
  • Kats LJ, Nelssen JL, Tokach MD, Goodband RD, Hansen JA, Laurin JL. The effect of spray-dried porcine plasma on growth performance in the early-weaned pig. J Anim.Sci 1994;72:2075-81.